Extracorporeal gas exchange for acute respiratory failure in adult patients: A systematic review. Critical Care 2015, 19: 99
Schmidt, M., et al.
http://ccforum.com/content/19/1/99
Mechanical ventilation remains the cornerstone of respiratory support for patients with acute respiratory failure. However, high pressure and volume associated with tidal ventilation are known to aggravate lung injury in this setting. Furthermore, profound gas-exchange abnormalities threatening patients’ lives can occur in the most severe forms of the disease despite recourse to conventional salvage therapies. Extracorporeal gas exchange devices, i.e., venovenous extracorporeal membrane oxygenation (ECMO) and extracorporeal carbon dioxide removal (ECCO2R), were developed more than 40 years ago to rescue these dying patients.
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