Cytomegalovirus infection in critically ill patients: a systematic
review. Critical Care 2009, 13: R68 [Article]
Osawa, R., Singh, N.
http://ccforum.com/content/13/3/R68
The precise role of cytomegalovirus (CMV) infection in contributing to outcomes in critically ill immunocompetent patients has not been fully defined. Studies in which critically ill
immunocompetent adults were monitored for CMV infection in the intensive care unit (ICU) were reviewed. Potential risk factors for CMV infection include sepsis, requirement of mechanical ventilation, and transfusions. CMV infection frequently occurs in critically ill immunocompetent patients and may be associated with poor outcomes.
A monthly current awareness service for NHS Critical Care staff, produced by the Library & Knowledge Service at East Cheshire NHS Trust.
Wednesday, 20 May 2009
Dexmedetomidine vs haloperidol in delirious, agitated, intubated patients
Dexmedetomidine vs. haloperidol in delirious, agitated, intubated
patients: a randomised open-label trial. Critical Care 2009 13:R75 [Journal article]
Reade, M.C., O'Sullivan, K., Bates, S., Goldsmith, D., StJ Ainslie, W.R., Bellomo, R.
http://ccforum.com/content/13/3/R75
Agitated delirium is common in patients undergoing mechanical ventilation, and is often treated with haloperidol despite concerns about safety and efficacy. Use of conventional sedatives to control agitation can preclude extubation. Dexmedetomidine, a novel sedative and anxiolytic agent, may have particular utility in these patients. We sought to compare the efficacy of haloperidol and
dexmedetomidine in facilitating extubation. In this preliminary pilot study, we found dexmedetomidine a promising agent for the treatment of ICU-associated delirious agitation, and we suggest this warrants further testing in a definitive double-blind multi-centre trial.
patients: a randomised open-label trial. Critical Care 2009 13:R75 [Journal article]
Reade, M.C., O'Sullivan, K., Bates, S., Goldsmith, D., StJ Ainslie, W.R., Bellomo, R.
http://ccforum.com/content/13/3/R75
Agitated delirium is common in patients undergoing mechanical ventilation, and is often treated with haloperidol despite concerns about safety and efficacy. Use of conventional sedatives to control agitation can preclude extubation. Dexmedetomidine, a novel sedative and anxiolytic agent, may have particular utility in these patients. We sought to compare the efficacy of haloperidol and
dexmedetomidine in facilitating extubation. In this preliminary pilot study, we found dexmedetomidine a promising agent for the treatment of ICU-associated delirious agitation, and we suggest this warrants further testing in a definitive double-blind multi-centre trial.
Model for predicting short-term mortality of severe sepsis
Model for predicting short-term mortality of severe sepsis. Critical Care 2009, 13:R72 [journal article].
Adrie, C., Francais, A., Alvarez-Gonzalez, A., Mounier, R., Azoulay, E., Zahar, J.R., Clec'h, C., Godgran-Toledano, D., Hammer, L., Descorps-Declere, A., Jamali, S., Timsit, J.F.
http://ccforum.com/content/13/3/R72
Development of a prognostic model for predicting 14-day mortality in ICU patients with severe sepsis.
Adrie, C., Francais, A., Alvarez-Gonzalez, A., Mounier, R., Azoulay, E., Zahar, J.R., Clec'h, C., Godgran-Toledano, D., Hammer, L., Descorps-Declere, A., Jamali, S., Timsit, J.F.
http://ccforum.com/content/13/3/R72
Development of a prognostic model for predicting 14-day mortality in ICU patients with severe sepsis.
Risk factors for delirium in intensive care patients: a prospective cohort study
Risk factors for delirium in intensive care patients: a prospective cohort study. Critical Care 2009, 13:R77 [journal article]
Van Rompaey, B., Elseviers, M.M., Schuurmans, M.J., Shortridge-Baggett, L.M., Truijen, S., Bossaert, L.
http://ccforum.com/content/13/3/R77
This multicenter study indicated risk factors for delirium in the intensive care unit related to patient characteristics, chronic pathology, acute illness and the environment. Several factors are suitable for preventive action.
Van Rompaey, B., Elseviers, M.M., Schuurmans, M.J., Shortridge-Baggett, L.M., Truijen, S., Bossaert, L.
http://ccforum.com/content/13/3/R77
This multicenter study indicated risk factors for delirium in the intensive care unit related to patient characteristics, chronic pathology, acute illness and the environment. Several factors are suitable for preventive action.
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