Methicillin-resistant Staphylococcus aureus central line-associated bloodstream infections in US intensive care units, 1997-2007.
Burton DC, Edwards JR, Horan TC, Jernigan JA, Fridkin SK.JAMA. 2009
Feb 18;301(7):727-36. PMID: 19224749
[PubMed - indexed for MEDLINE]
Related Articles
Showing posts with label JAMA [journal]. Show all posts
Showing posts with label JAMA [journal]. Show all posts
Tuesday, 7 April 2009
Tuesday, 24 February 2009
A new era for sedation in ICU patients.
A new era for sedation in ICU patients.
Wunsch H, Kress JP.
JAMA. 2009 Feb 4;301(5):542-4.
Epub 2009 Feb 2. No abstract available.
[PubMed - indexed for MEDLINE]Related Articles
Wunsch H, Kress JP.
JAMA. 2009 Feb 4;301(5):542-4.
Epub 2009 Feb 2. No abstract available.
[PubMed - indexed for MEDLINE]Related Articles
Dexmedetomidine vs midazolam for sedation of critically ill patients: a randomized trial.
Dexmedetomidine vs midazolam for sedation of critically ill patients: a randomized trial.
Riker RR, Shehabi Y, Bokesch PM, Ceraso D, Wisemandle W, Koura F, Whitten P, Margolis BD, Byrne DW, Ely EW, Rocha MG;
SEDCOM (Safety and Efficacy of Dexmedetomidine Compared With Midazolam)
Study Group. JAMA. 2009 Feb 4;301(5):489-99.
Epub 2009 Feb 2. PMID: 19188334 [PubMed - indexed for MEDLINE]
Related Articles
Riker RR, Shehabi Y, Bokesch PM, Ceraso D, Wisemandle W, Koura F, Whitten P, Margolis BD, Byrne DW, Ely EW, Rocha MG;
SEDCOM (Safety and Efficacy of Dexmedetomidine Compared With Midazolam)
Study Group. JAMA. 2009 Feb 4;301(5):489-99.
Epub 2009 Feb 2. PMID: 19188334 [PubMed - indexed for MEDLINE]
Related Articles
Monday, 17 November 2008
Mobilizing patients in the intensive care unit: improving neuromuscular weakness and physical function.
Needham DM. Related Articles, LinkOut
JAMA. 2008 Oct 8;300(14):1685-90. PMID: 18840842 [PubMed - indexed for MEDLINE]
JAMA. 2008 Oct 8;300(14):1685-90. PMID: 18840842 [PubMed - indexed for MEDLINE]
Tuesday, 28 October 2008
Mobilizing patients in the intensive care unit: improving neuromuscular weakness and physical function.
1: JAMA. 2008 Oct 8;300(14):1685-90. LinkOut
Needham DM.
Division of Pulmonary and Critical Care Medicine, and Department of Physical Medicine and Rehabilitation, Johns Hopkins University, Baltimore, Maryland 21205, USA. dale.needham@jhmi.edu
Early mobilization of patients in the hospital and the intensive care unit has a strong historical precedent. However, in more recent times, deep sedation and bed rest have been part of routine medical care for many mechanically ventilated patients. A growing body of literature demonstrates that survivors of severe critical illness commonly have significant and prolonged neuromuscular complications that impair their physical function and quality of life after hospital discharge. Bed rest, and its associated mechanisms, may play an important role in the pathogenesis of neuromuscular weakness in critically ill patients. A new approach for managing mechanically ventilated patients includes reducing deep sedation and increasing rehabilitation therapy and mobilization soon after admission to the intensive care unit. Emerging research in this field provides preliminary evidence supporting the safety, feasibility, and potential benefits of early mobilization in critical care medicine.
PMID: 18840842 [PubMed - in process]
Needham DM.
Division of Pulmonary and Critical Care Medicine, and Department of Physical Medicine and Rehabilitation, Johns Hopkins University, Baltimore, Maryland 21205, USA. dale.needham@jhmi.edu
Early mobilization of patients in the hospital and the intensive care unit has a strong historical precedent. However, in more recent times, deep sedation and bed rest have been part of routine medical care for many mechanically ventilated patients. A growing body of literature demonstrates that survivors of severe critical illness commonly have significant and prolonged neuromuscular complications that impair their physical function and quality of life after hospital discharge. Bed rest, and its associated mechanisms, may play an important role in the pathogenesis of neuromuscular weakness in critically ill patients. A new approach for managing mechanically ventilated patients includes reducing deep sedation and increasing rehabilitation therapy and mobilization soon after admission to the intensive care unit. Emerging research in this field provides preliminary evidence supporting the safety, feasibility, and potential benefits of early mobilization in critical care medicine.
PMID: 18840842 [PubMed - in process]
Associations Between End-of-Life Discussions, Patient Mental Health, Medical Care Near Death, and Caregiver Bereavement Adjustment
Wednesday, October 22, 2008
Extract from http://runningahospital.blogspot.com/
Associations Between End-of-Life Discussions, Patient Mental Health, Medical Care Near Death, and Caregiver Bereavement Adjustment
Alexi A. Wright, MD; Baohui Zhang, MS; Alaka Ray, MD; Jennifer W. Mack, MD, MPH; Elizabeth Trice, MD, PhD; Tracy Balboni, MD, MPH; Susan L. Mitchell, MD; Vicki A. Jackson, MD, MPH; Susan D. Block, MD; Paul K. Maciejewski, PhD; Holly G. Prigerson, PhDJAMA. 2008;300(14):1665-1673.
Context
Talking about death can be difficult. Without evidence that end-of-life discussions improve patient outcomes, physicians must balance their desire to honor patient autonomy against a concern of inflicting psychological harm.
Objective: To determine whether end-of-life discussions with physicians are associated with fewer aggressive interventions.Design, Setting, and ParticipantsA US multisite, prospective, longitudinal cohort study of patients with advanced cancer and their informal caregivers (n = 332dyads), September 2002-February 2008. Patients were followed up from enrollment to death, a median of 4.4 months later. Bereaved caregivers' psychiatric illness and quality of life was assessed a median of 6.5 months later.
Main Outcome Measures Aggressive medical care (eg, ventilation, resuscitation) and hospice in the final week of life. Secondary outcomes included patients' mental health and caregivers' bereavement adjustment.ResultsOne hundred twenty-three of 332 (37.0%) patients reported having end-of-life discussions before baseline.... After propensity-score weighted adjustment, end-of-life discussions were associated with lower rates of ventilation... resuscitation ... ICU admission ... and earlier hospice enrollment. In adjusted analyses, more aggressive medical care was associated with worse patient quality of life ... and higher risk of major depressive disorder in bereaved caregivers ... whereas longer hospice stays were associated with better patient quality of life .... Better patient quality of life was associated with better caregiver quality of life at follow-up....
Conclusions
End-of-life discussions are associated with less aggressive medical care near death and earlier hospice referrals. Aggressive care is associated with worse patient quality of life and worse bereavement adjustment.
Posted by Paul Levy at 10/22/2008 08:11:00 PM 3 comments
Extract from http://runningahospital.blogspot.com/
Associations Between End-of-Life Discussions, Patient Mental Health, Medical Care Near Death, and Caregiver Bereavement Adjustment
Alexi A. Wright, MD; Baohui Zhang, MS; Alaka Ray, MD; Jennifer W. Mack, MD, MPH; Elizabeth Trice, MD, PhD; Tracy Balboni, MD, MPH; Susan L. Mitchell, MD; Vicki A. Jackson, MD, MPH; Susan D. Block, MD; Paul K. Maciejewski, PhD; Holly G. Prigerson, PhDJAMA. 2008;300(14):1665-1673.
Context
Talking about death can be difficult. Without evidence that end-of-life discussions improve patient outcomes, physicians must balance their desire to honor patient autonomy against a concern of inflicting psychological harm.
Objective: To determine whether end-of-life discussions with physicians are associated with fewer aggressive interventions.Design, Setting, and ParticipantsA US multisite, prospective, longitudinal cohort study of patients with advanced cancer and their informal caregivers (n = 332dyads), September 2002-February 2008. Patients were followed up from enrollment to death, a median of 4.4 months later. Bereaved caregivers' psychiatric illness and quality of life was assessed a median of 6.5 months later.
Main Outcome Measures Aggressive medical care (eg, ventilation, resuscitation) and hospice in the final week of life. Secondary outcomes included patients' mental health and caregivers' bereavement adjustment.ResultsOne hundred twenty-three of 332 (37.0%) patients reported having end-of-life discussions before baseline.... After propensity-score weighted adjustment, end-of-life discussions were associated with lower rates of ventilation... resuscitation ... ICU admission ... and earlier hospice enrollment. In adjusted analyses, more aggressive medical care was associated with worse patient quality of life ... and higher risk of major depressive disorder in bereaved caregivers ... whereas longer hospice stays were associated with better patient quality of life .... Better patient quality of life was associated with better caregiver quality of life at follow-up....
Conclusions
End-of-life discussions are associated with less aggressive medical care near death and earlier hospice referrals. Aggressive care is associated with worse patient quality of life and worse bereavement adjustment.
Posted by Paul Levy at 10/22/2008 08:11:00 PM 3 comments
Tuesday, 9 September 2008
Benefits and risks of tight glucose control in critically ill adults: a meta-analysis
Soylemez Wiener R, Wiener DC, Larson RJ. Related Articles, LinkOut
Benefits and risks of tight glucose control in critically ill adults: a meta-analysis.
JAMA. 2008 Aug 27;300(8):933-44. PMID: 18728267 [PubMed - indexed for MEDLINE]
Benefits and risks of tight glucose control in critically ill adults: a meta-analysis.
JAMA. 2008 Aug 27;300(8):933-44. PMID: 18728267 [PubMed - indexed for MEDLINE]
Monday, 7 July 2008
Electromagnetic Interference From Radio Frequency Identification Inducing Potentially Hazardous Incidents in Critical Care Medical Equipment
JAMA - Journal of the American Medical Association From Publisher From Free Medical Journals . com (/1998 - /Embargo: 6 months)
From HighWire article] [author(s)]
From HighWire article] [author(s)]
Tuesday, 3 June 2008
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