Outcome effectiveness of the severe sepsis resuscitation bundle with addition of lactate clearance as a bundle item

Outcome effectiveness of the severe sepsis resuscitation bundle with addition of lactate clearance as a bundle item: a multi-national evaluation. Critical Care 2011, 15:R229.

Nguyen, HB., et al.

Implementation of the Surviving Sepsis Campaign (SSC) guidelines has been associated with improved outcome in patients with severe sepsis. Resolution of lactate elevations or lactate clearance has also been shown to be associated with outcome. The purpose of this study was to examine the compliance and effectiveness of the SSC resuscitation bundle with the addition of lactate clearance.