Sedation and renal impairment in critically ill patients

Sedation and renal impairment in critically ill patients: a post-hoc analysis of a randomized trial. Critical Care 2011, 15:R119

Strom T, Johansen RR, Prahl JR and Toft P.

http://ccforum.com/content/15/3/R119

Not sedating critically ill patients reduces the time patients receive mechanical ventilation, decreases the time in the intensive care department and reduces the total hospital length of stay. We hypothesized that no sedation improves hemodynamic stability, decreases the need for vasoactive drugs, diminishes the need for extra fluids and lowers the risk of acute kidney injury.