Is cytomegalovirus reactivation increasing the mortality of patients with severe sepsis?

Is cytomegalovirus reactivation increasing the mortality of patients with severe sepsis? Critical Care 2011 15:138

Kalil AC and Florescu DF.

Critically ill patients who are immunocompetent before intensive care unit (ICU) admission may also become more prone to develop active CMV infection if they have prolonged hospitalizations, high disease severity, and severe sepsis. The development of active CMV disease has been associated with a significant higher risk of death in several previous studies. This Critical Care edition brings a new study by Heininger et al in which they found that patients with severe sepsis who developed active CMV infection had a significantly longer ICU and hospital stays, prolonged mechanical ventilation, but no changes in mortality compared to patients without CMV infection.