Myocardial dysfunction assessed by speckle-tracking in good-grade subarachnoid hemorrhage patients (WFNS 1–2): a prospective observational study

by Hugues de Courson, Grégoire Chadefaux, Alexandre Loiseau, Delphine Georges and Matthieu Biais 

Critical Care volume 27, Article number: 455 (2023) Published: 21 November 2023

Background

Cardiac complications due to non-traumatic subarachnoid hemorrhage (SAH) are usually described using classical echocardiographic evaluation. Strain imaging appears to have better sensitivity than standard echocardiographic markers for the diagnosis of left ventricular dysfunction. The aim of this study was to determine the prevalence of cardiac dysfunction defined as a Global Longitudinal Strain (GLS) ≥  − 20% in patients with good-grade SAH (WFNS 1 or 2).

Methods

Seventy-six patients with good-grade SAH were prospectively enrolled and analyzed at admission for neurocritical care. Transthoracic echocardiography was performed on days 1, 3, and 7 after hemorrhage. Routine measurements, including left ventricular ejection fraction (LVEF), were performed, and off-line analysis was performed by a blinded examiner, to determine 2-, 3-, and 4-cavity longitudinal strain and left ventricular GLS. GLS was considered altered if it was ≥  − 20%, we also interested the value of ≥  − 17%. LVEF was considered altered if it was < 50%.

Results

On day 1, 60.6% of patients had GLS ≥  − 20% and 21.2% of patient had GLS ≥  − 17%. In comparison, alteration of LVEF was present in only 1.7% of patients. The concordance rate between LVEF < 50% and GLS ≥  − 20% and LVEF ≥ 50% and GLS <  − 20% was 46%.

Conclusion

Strain imaging showed a higher prevalence (60.6%) of left ventricular dysfunction during the acute phase of good-grade SAH (WFNS 1 or 2) than previously described.