by Fabio Silvio Taccone, Edoardo Picetti and Jean-Louis
Vincent
Critical Care volume 24,
Article number: 6 (2020)
Targeted temperature management (TTM) is a complex
intervention used with the aim of minimizing post-anoxic injury and improving
neurological outcome after cardiac arrest. There is large variability in the
devices used to achieve cooling and in protocols (e.g., for induction, target
temperature, maintenance, rewarming, sedation, management of post-TTM fever).
This variability can explain the limited benefits of TTM that have sometimes
been reported. We therefore propose the concept of “high-quality TTM” as a way
to increase the effectiveness of TTM and standardize its use in future
interventional studies.
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