Effects of fluid administration on renal perfusion in critically ill patients

Effects of fluid administration on renal perfusion in critically ill patients

Critical Care 2015, 19:250  doi:10.1186/s13054-015-0963-0

Mouhamed Djahoum Moussa et al

http://ccforum.com/content/19/1/250

Fluid administration is a first-line therapy for acute kidney injury associated with circulatory failure. Although aimed at increasing renal perfusion in these patients, this intervention may improve systemic hemodynamics without necessarily ameliorating intra-renal flow distribution or urine output. We used Doppler techniques to investigate the effects of fluid administration on intra-renal hemodynamics and the relationship between changes in renal hemodynamics and urine output. We hypothesized that, compared to systemic hemodynamic variables, changes in renal hemodynamics would better predict increase in urine output after fluid therapy.