Statins and delirium during critical illness

Statins and delirium during critical illness: A multicenter, prospective cohort study. Critical Care Medicine Aug. 2014, Vol. 42(8), p.1899-1909.

Morandi, A., et al.

http://journals.lww.com/ccmjournal/Abstract/2014/08000/Statins_and_Delirium_During_Critical_Illness___A.18.aspx

Since statins have pleiotropic effects on inflammation and coagulation that may interrupt delirium pathogenesis, we tested the hypotheses that statin exposure is associated with reduced delirium during critical illness, whereas discontinuation of statin therapy is associated with increased delirium.