Initial use of one or two antibiotics for critically ill patients with community-acquired pneumonia

Initial use of one or two antibiotics for critically ill patients with community-acquired pneumonia: Impact on survival and bacterial resistance. Critical care, Nov 2013, Vol. 17(6), R:267.

Adrie, C., et al.

http://ccforum.com/content/17/6/R265/abstract

Several guidelines recommend initial empirical treatment with two antibiotics instead of one to decrease mortality in community-acquired pneumonia (CAP) requiring intensive-care-unit (ICU) admission. We compared the impact on 60-day mortality of using one or two antibiotics. We also compared the rates of nosocomial pneumonia and multidrug-resistant bacteria.