Therapeutic drug monitoring of Amikacin in septic patients. Critical care, July 2013, 17: R165.
Duszynska, W., et al.
http://ccforum.com/content/17/4/R165/abstract
Use of higher than standard doses of amikacin (AMK) has been proposed during sepsis, especially to treat less susceptible bacterial strains. However, few data are available on drug concentrations during prolonged therapy and on potential adverse events related to this strategy.
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