Targeted versus universal decolonization to prevent ICU infection

Targeted versus universal decolonization to prevent ICU infection. New england journal of medicine, May 2013 [published online]  DOI: 10.1056/NEJMoa1207290

Huang, S.S., et al.

http://www.nejm.org/doi/full/10.1056/NEJMoa1207290?af=R&rss=currentIssue#t=articleTop

Health care–associated infection is a leading cause of preventable illness and death and often results from colonizing bacteria that overcome body defenses. Among the pathogens causing health care–associated infection, methicillin-resistant Staphylococcus aureus (MRSA) has been given priority as a target of reduction efforts because of its virulence and disease spectrum, multidrug-resistant profile, and increasing prevalence in health care settings, particularly among patients in the intensive care unit (ICU).