Impaired cerebrovascular autoregulation in patients with severe sepsis

Impaired cerebrovascular autoregulation in patients with severe sepsis and sepsis-associated delirium.  Critical Care 2012, 16:R181.

Schramm, P., et al.

http://ccforum.com/content/16/5/R181/abstract

Sepsis-associated delirium (SAD) increases morbidity in septic patients and, therefore, factors contributing to SAD should be further characterized. One possible mechanism might be the impairment of cerebrovascular autoregulation (AR) by sepsis, leading to cerebral hypo- or hyperperfusion in these haemodynamically unstable patients.