Diacerhein attenuates the inflammatory response and improves survival in a model of severe sepsis. Critical care, August 2012, 16(4): R158
Calisto, K.L., et al.
http://ccforum.com/content/16/4/R158/abstract
Hyperglycemia and insulin resistance has been associated with a worse outcome in sepsis. Although tight glycaemic control through insulin therapy has been shown to reduce morbidity and mortality rates, the effect of intensive insulin therapy in patients with severe sepsis is controversial because of the increased risk of serious adverse events related to hypoglycemia.
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