Hypoglycemia in the critically ill: how low is too low? Mayo clinic proceedings, March 2010, Vol. 85(3), p. 215-216.
Krinsley, J.S.
http://www.mayoclinicproceedings.com/content/85/3/215.full
Tight glycemic control in critically ill patients became a therapeutic paradigm after the 2001 publication of a landmark single-center interventional trial in Leuven, Belgium, (ie, “Leuven 1”) that targeted euglycemia in a population of mechanically ventilated patients in a surgical intensive care unit (ICU).
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