Probiotics in the critically ill: A systematic review of the randomized trial evidence. Critical care medicine, December 2012, Vol. 40(12), p.3290-3302.
Petrof, E.O., et al.
http://journals.lww.com/ccmjournal/Abstract/2012/12000/Probiotics_in_the_critically_ill___A_systematic.22.aspx
Critical illness results in changes to the microbiology of the gastrointestinal tract, leading to a loss of commensal flora and an overgrowth of potentially pathogenic bacteria. Administering certain strains of live bacteria (probiotics) to critically ill patients may restore balance to the microbiota and have positive effects on immune function and gastrointestinal structure and function. The purpose of this systematic review was to evaluate the effect of probiotics in critically ill patients on clinical outcomes.
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