Association Between Arterial Hyperoxia and Outcome in Subsets of Critical Illness: A Systematic Review, Meta-Analysis, and Meta-Regression of Cohort Studies

Association Between Arterial Hyperoxia and Outcome in Subsets of Critical Illness: A Systematic Review, Meta-Analysis, and Meta-Regression of Cohort Studies

Critical Care Medicine: July 2015 - Volume 43 - Issue 7 - p 1508–1519 doi:10.1097/CCM.0000000000000998

Helmerhorst, HJF et al

http://journals.lww.com/ccmjournal/Fulltext/2015/07000/Association_Between_Arterial_Hyperoxia_and_Outcome.18.aspx

Objective: Oxygen is vital during critical illness, but hyperoxia may harm patients. Our aim was to systematically evaluate the methodology and findings of cohort studies investigating the effects of hyperoxia in critically ill adults.  A meta-analysis and meta-regression analysis of cohort studies published between 2008 and 2015 was conducted.