Effects of etomidate on complications related to intubation and on mortality in septic shock patients treated with hydrocortisone: a propensity score analysis. Critical care, November 2012, Vol. 16(6): R224.
Jung, B., et al.
http://ccforum.com/content/16/6/R224/abstract
Endotracheal intubation in the intensive care unit is associated with a high incidence of complications. Etomidate use is debated in septic shock because it increases the risk of critical illness-related corticosteroid insufficiency, which may impact outcome. We hypothesized that hydrocortisone, administered in all septic shock in our intensive care unit, and may counteract some negative effects of etomidate. The aim of our study was to compare septic shock patients who received etomidate vs another induction drug both on the short-term safety and the long-term outcomes.
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