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Breast Surgery

Tuesday 27 July 2021

Why and how do we need comprehensive international clinical epidemiology of ARDS?

 

Why and how do we need comprehensive international clinical epidemiology of ARDS?

By: Gianni TognoniLuigi Vivona & Antonio Pesenti 

Intensive Care Medicine Published: 03 July 2021

One of the most evident weaknesses of scientific and public health strategies in the management of the coronavirus disease 2019 (COVID-19) pandemic is certainly the scarcity of robust epidemiological data, not limited to the quali-quantitative descriptions of patient populations and their outcomes, specifically in the hardly comparable ICU settings of care, but aimed at what has become the core and the vocation of a clinically oriented epidemiological investigation. Clinical data collected and analysed with sound methodological criteria are the essential source of information, closely complementary to physio-pathological data for a better understanding of the causes of the outcomes of critical and still uncertain clinical conditions.

The substantial absence of this type of epidemiology has suggested a broader question: whether and how far the failure documented in publications relating to the ICU phases of Covid-19 coincides with the state of the art also for the acute respiratory distress syndrome (ARDS), closely overlapping the severe pulmonary involvement seen in a small but dramatic fraction of the Covid-19-infected population.

We felt that a targeted survey of the clinical epidemiological literature could provide an overview of the methodological strengths and weaknesses of recent research, and serve as an informed suggestion as to most practicable strategies…

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