Sepsis-3: What is the Meaning of a Definition?
Critical Care Medicine
Marshall, J C
The recent publication of Sepsis-3–the latest iteration of an effort to define sepsis–has evoked an impressive response . To date it has been viewed more than one million times on the JAMA
website, making it one of the most highly accessed articles there in
recent years. It has also generated a flurry of commentaries–some
supportive, some opposing, and almost all thoughtful .
Indeed recognizing as the original paper did that the new definition is
simply the next step in the evolution of a challenging process, the
controversy is as important as the Sepsis-3 document in clarifying what
has been accomplished and what remains undone.