Trial of early, goal-directed resuscitation for septic shock

Trial of early, goal-directed resuscitation for septic shock. NEJM, March 2015

Mouncey, P.R., et al.

http://www.nejm.org/doi/full/10.1056/NEJMoa1500896#t=article

The incidence of severe sepsis and septic shock in adults is estimated to range from 56 to 91 per 100,000 population per year. Affected patients have high rates of death, complications, and resource utilization.