Minimizing antibiotic exposure in the ICU: in search of the optimal strategy. Critical Care, Oct 2014, 18:613
Brun-Buisson, C.
http://ccforum.com/content/18/5/613
The current paradigm for antibiotic management in critically ill patients is to initiate broad-spectrum therapy followed by de-escalation based on microbiological results. Routine screening cultures may allow better targeting and reduce unnecessary exposure to antibiotics.
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