Should heparin-binding protein levels be routinely monitored in patients with severe sepsis and septic shock? Critical care, 2012, Vol. 16: 133
Mnull, H. and Onull, B.
Heparin-binding protein (HBP), also known as azurocidin, has multiple functions in the inflammatory process, especially during severe infections. Beside its antimicrobial properties, HBP may induce vascular leakage leading to extravascular efflux, which is an important pathophysiologic event in the development of septic shock.