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Friday 31 July 2009

Hydrocortisone therapy for patients with septic shock

Hydrocortisone therapy for patients with septic shock. New england journal of medicine, Vol 358 (2), January 2008 [journal article]

Sprung, C.L., et al.

http://content.nejm.org/cgi/reprint/358/2/111.pdf


Hydrocortisone is widely used in patients with septic shock, even though a survival benefit has been reported only in patients who remained hypotensive after fluid and vasopressor resuscitation and whose plasma cortisol levels did not rise appropriately after the administration of corticotropin.

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