Cunningham , M . C . ; Reilly , J . P . ; Lavie , C . J . ; Sundell , E . T .
Proquest NHS (10/1998 - 02/2003)
Page: 20-26 Vol/Issue: 2008 ; VOL 40 ; PART 10
ISSN Print: 0013-6654
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Coronary heart disease (CHD) is the leading cause of death in the United States, and unstable angina (UA) and non-ST-segment-elevation myocardial infarction (NSTEMI) are often acute manifestations of this disease. Each year, UA and NSTEMI affect more than 1.2 million people in this country, causing significant morbidity and mortality.
In 2007, the American College of Cardiology (ACC) and American Heart Association (AHA) released updated guidelines for the management of patients with UA and NSTEMI, revised from previous guidelines due to a growing body of evidence from clinical trials. The new guidelines were developed by experts from the ACC and the AHA, in collaboration with the American College of Emergency Physicians. The writing committee performed a literature review and made recommendations based on the strength of existing evidence. The committee created classifications (classes I, IIa, IIb, and III) and levels of evidence for each recommendation in order to estimate both the size and certainty of an effect for each recommendation.
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